What role does estrogen play in the context of fibroids?

Estrogen plays a significant role in the growth of uterine fibroids, which are noncancerous tumors that develop in the uterus. High levels of estrogen, particularly during the reproductive years, can stimulate the growth of these fibroids. This hormone promotes cellular proliferation and enhances the size and number of fibroids, especially during periods of hormonal fluctuations such as pregnancy or when hormone replacement therapy is administered. As a result, the presence of estrogen can lead to the rapid growth of fibroids, which may contribute to symptoms such as abnormal uterine bleeding, pelvic pain, and pressure on surrounding organs. Understanding the relationship between estrogen and fibroids is essential for managing symptoms and treatment options.